Increased MYC copy number is associated with poor prognosis in CLL. The MYC proto-oncogene is considered to contribute to CLL pathogenesis. Some clinical and biological features indicating an unfavorable course of the disease were found in ionizing radiation (IR) - related chronic lymphocytic leukemia (CLL) patients. 2Department of Hematology, National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Kyiv 02000, Ukraine. 1Department of Clinical Immunology, National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Kyiv 02000, Ukraine.MYC copy number and mRNA expression in chronic lymphocytic leukemia patients exposed to ionizing radiation due to the Chornobyl NPP accidentīilous N.* 1, Abramenko I.
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